51 CD8+ TRM cells can limit the entry of Mtb into lung tissue by killing contaminated macrophages, and result in protective innate and adaptive immune responses by secreting IFN-?, TNF-?, and IL-2. When these cytokines are blocked, this protective immune responses disappear fully.14,fifty two Whilst

[fifty five] Mycobacteria have an outer membrane lipid bilayer.[fifty six] If a Gram stain is executed, MTB either stains quite weakly "Gram-favourable" or won't keep dye as a result of the superior lipid and mycolic acid written content of its mobile wall.[57] MTB can endure weak disinfectants and